At this relaxed neighborhood hangout - which also boasts a large outdoor patio - you’ll find a great selection of seasonal shared plates (think Peruvian style sashimi and handmade pasta), plus craft beers and a boutique wine list spanning new and old world varietals by the glass and bottle.

Sleek design details and a foot-tapping playlist set the scene for a sophisticated dinner-come-low-key-club-vibe at Madison. Order share plates for the table – like brie with apricot habanero honey, portabella fries and the beet-cured salmon crudo – before working your way through the cocktail list, which showcases original and classic drinks alongside four barrel-aged options. 

For an elevated nightlife experience with cocktails in sophisticated surrounds head to Oxford Social Club, located beneath the glam Pendry San Diego. Recline on plush furnishings while enjoying the extensive craft cocktail program or dancing the night away, at least until 2 a.m.

Nestled in one of San Diego’s most picturesque neighborhoods whimsical wine bar The Rose is a perfect place to gather the girlfriends for an evening of thoughtfully sourced vino and light bites. The menu showcases varietals from French Champagne and mourvedre-grananche blends to chenin blanc and viogner – all retail purchases can be opened for a $10 corkage fee.

Located in San Diego’s hip East Village, Café Chloe is a great place to kick-start girls’ night. Enjoy an award-winning menu of updated French bistro classics and boutique wines in Parisian-inspired digs, then take in a digestif on the charming sidewalk patio before making a short stroll towards the lights and action of the Gaslamp.

What better way to kick off girls night than with a flagship tasting flight ($10) at downtown’s modish new distillery? Afterwards, stay and sample one of 15 craft cocktails: refreshed twice every season current tipples include the Shirley Rose (Sunday Gin, rose petal cordial, fresh lemon) and Daddy Don’t Make Dinner (Y&Y vodka, blackberries, lemon, honey, topo chico).

Stop in for a bottle and light bites with the girls at this cozy-yet-hipster warehouse space on India. Vino Carta offers up to 12 wines by the glass with a menu focused on small family-run producers and natural/organic wines. From a broad international selection two standouts include the Spanish Vendrell Rived 'Miloca' Carinyena and a 2015 Loire Valley Sancerre Rose.

Dig into rotisserie chicken, small bites like calamari and arancini, homemade pasta and entrees such as a whole roasted branzino with the girls at this Little Italy neighborhood gem. The wine list boasts regional and global selections - with a leaning towards Italian varietals like Tuscan Red, Nebbiolo and Barbera – all best enjoyed on the sidewalk patio.

Located atop the Andaz Hotel, The Rooftop by STK supplies stunning city views, creative regional cuisine and some killer cocktails making it one of San Diego's premier rooftop destinations for the ultimate city sophisticate girls night out.